Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches.

@article{Alexander1997AntifungalRT,
  title={Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches.},
  author={Barbara Dudley Alexander and John R Perfect},
  journal={Drugs},
  year={1997},
  volume={54 5},
  pages={
          657-78
        }
}
Medical advances have led to increased numbers of immunocompromised patients living longer. Coinciding with this increase in the immunocompromised patient population is an increase in the number of clinically significant fungal infections. Unfortunately, widespread use of the limited numbers of antifungal agents to treat these infections has led to the development of drug resistance. Thus, in an attempt to sort out the mechanisms of resistance for each of the systemically useful antifungal… CONTINUE READING
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