Antifungal properties of selective serotonin reuptake inhibitors against Aspergillus species in vitro.

@article{LassFlrl2001AntifungalPO,
  title={Antifungal properties of selective serotonin reuptake inhibitors against Aspergillus species in vitro.},
  author={Cornelia Lass-Fl{\"o}rl and Manfred Paul Dierich and Dietmar Fuchs and E. Semenitz and Ilse H Jenewein and Maximilian Ledochowski},
  journal={The Journal of antimicrobial chemotherapy},
  year={2001},
  volume={48 6},
  pages={775-9}
}
This study investigated the fungicidal activity of selective serotonin reuptake inhibitors (SSRIs) against clinical isolates of Aspergillus fumigatus (n = 11), Aspergillus flavus (n = 9), Aspergillus terreus (n = 10) and Candida parapsilosis (ATCC 22019). The common drugs fluoxetine, seroxate, sertraline, paroxetine and reboxetine were applied in a broth microdilution test. In addition, we examined whether a post-antibiotic effect occurs following short exposure to the drugs. The various SSRIs… CONTINUE READING