Antifungal peptides: To be or not to be membrane active.

@article{Rautenbach2016AntifungalPT,
  title={Antifungal peptides: To be or not to be membrane active.},
  author={Marina Rautenbach and Anscha Mari Troskie and Johan Arnold Vosloo},
  journal={Biochimie},
  year={2016},
  volume={130},
  pages={132-145}
}
Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have alternative targets. Fungal membranes share many characteristics with mammalian membranes with only a few differences, such as differences in sphingolipids, phosphatidylinositol (PI) content and the main sterol is ergosterol. Fungal membranes are also more negative and… CONTINUE READING