Antifungal interactions within the triple combination of amphotericin B, caspofungin and voriconazole against Aspergillus species.

@article{OShaughnessy2006AntifungalIW,
  title={Antifungal interactions within the triple combination of amphotericin B, caspofungin and voriconazole against Aspergillus species.},
  author={Elizabeth M O'Shaughnessy and Joseph Meletiadis and Theodouli Stergiopoulou and Joanne P Demchok and Thomas J Walsh},
  journal={The Journal of antimicrobial chemotherapy},
  year={2006},
  volume={58 6},
  pages={1168-76}
}
OBJECTIVES The in vitro effects of caspofungin combined with voriconazole and amphotericin B were tested in triplicate experiments against nine clinical isolates of Aspergillus fumigatus, Aspergillus flavus and Aspergillus terreus. METHODS The isolates were tested against a range of concentrations of voriconazole (0.015-1.0 mg/L), caspofungin (0.125-256 mg/L) and five concentrations of amphotericin B (0.1-0.5 mg/L) with a microdilution chequerboard method based on the CLSI M38-A reference… CONTINUE READING

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