Antifungal drug development: challenges, unmet clinical needs, and new approaches.

@article{Roemer2014AntifungalDD,
  title={Antifungal drug development: challenges, unmet clinical needs, and new approaches.},
  author={Terry Roemer and Damian J Krysan},
  journal={Cold Spring Harbor perspectives in medicine},
  year={2014},
  volume={4 5}
}
Invasive, life-threatening fungal infections are an important cause of morbidity and mortality, particularly for patients with compromised immune function. The number of therapeutic options for the treatment of invasive fungal infections is quite limited when compared with those available to treat bacterial infections. Indeed, only three classes of molecules are currently used in clinical practice and only one new class of antifungal drugs has been developed in the last 30 years. Here we… CONTINUE READING

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