Antifungal constituents of Melicope borbonica

  title={Antifungal constituents of Melicope borbonica},
  author={Henrik Toft Simonsen and Anne Adsersen and Paul D. Bremner and Michael Heinrich and Ulla Wagner Smitt and Jerzy W. Jaroszewski},
  journal={Phytotherapy Research},
Fractionation of extracts of the leaves of Melicope borbonica (syn. Euodia borbonica var. borbonica), a medicinal plant from the Réunion Island that is traditionally used for wound healing and other ailments, afforded an acetophenone (xanthoxylin) and two coumarins, scoparone and limettin, as the major constituents. All three compounds exhibited moderate antifungal activity against Candida albicans and Penicillium expansum, in accordance with the traditional use of the plant. Moreover, 2,4,6… 
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