Antifungal combination therapy with granulocyte colony-stimulating factor and fluconazole in experimental disseminated candidiasis

@article{Graybill1995AntifungalCT,
  title={Antifungal combination therapy with granulocyte colony-stimulating factor and fluconazole in experimental disseminated candidiasis},
  author={John Richard Graybill and R. Castillo Bocanegra and M. Luther},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1995},
  volume={14},
  pages={700-703}
}
The present studies were performed to determine whether any beneficial interaction results from combination therapy with recombinant human granulocyte colony-stimulating factor (GCSF) and fluconazole in disseminated candidiasis in mice. Fluconazole extended survival and reduced tissue counts. GCSF had no direct benefit, but GCSF combined with fluconazole… CONTINUE READING