• DOI:10.1111/J.2042-7158.1964.TB07482.X
Corpus ID: 26994446

Antifungal activity of some imidazole derivatives

@article{Ellis1964AntifungalAO,
  title={Antifungal activity of some imidazole derivatives},
  author={G. Ellis and C. Epstein and C. Fitzmaurice and L. Golberg and G. Lord},
  journal={Journal of Pharmacy and Pharmacology},
  year={1964},
  volume={16}
}

G. Ellis, C. Epstein, +2 authors G. Lord

Published 1964

Medicine, Chemistry

Journal of Pharmacy and Pharmacology

A series of 4(5)‐arylimidazoles and their N‐alkyl and other derivatives has been synthesised. Some of these compounds possessed good in vitro antifungal action, especially against strains of Trichophyton and less activity against Microsporum, Aspergillus and Candida strains; their activity against all mycological pathogens was reduced in the presence of serum. The three most active compounds are 1‐alkyl‐4‐(3,4‐dichlorophenyl)imidazoles in which the alkyl group is an n‐propyl, n‐butyl or… CONTINUE READING

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