Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo

@inproceedings{Munoz2017AntifungalAO,
  title={Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo},
  author={J. T. E. Munoz and Diego C P Rossi and Kelly Ishida and Cristina de Castro Spadari and M{\'a}rcia de Souza Carvalho Melhem and Daniel F. Garcia and Antonio Carlos Favero Caires and Carlos Pelleschi Taborda and Elaine Guadelupe Rodrigues},
  booktitle={Front. Microbiol.},
  year={2017}
}
Vulvovaginal and invasive candidiasis are frequent conditions in immunosuppressed individuals caused by Candida albicans and non-albicans Candida spp. Fluconazole and Amphotericin B are the main drugs used to fight the infection. However, resistance to fluconazole and other azole antifungal drugs is an important clinical problem that encourages the search for new therapeutic alternatives. In this work, we evaluate the antifungal activity of the biphosphinic cyclopalladate C7a in the in vitro… CONTINUE READING
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