Antifungal Activity of Gentamicin B1 against Systemic Plant Mycoses

  title={Antifungal Activity of Gentamicin B1 against Systemic Plant Mycoses},
  author={G. Banfalvi},
Background: Gentamicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora purpurea bacteria, effective against Gram-negative bacterial infections. Major fractions of the gentamicin complex (C1, C1a, C2, C2a) possess weak antifungal activity and one of the minor components (A, A1–A4, B, B1, X), gentamicin B1 was found to be a strong antifungal agent. Methods: This work uses in vitro and in vivo dilution methods to compare the antifusarial, antiaspergillic and… Expand
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Retrospective evaluation of in vitro effect of gentamicin B1 against Fusarium species
  • G. Banfalvi
  • Biology, Medicine
  • Applied Microbiology and Biotechnology
  • 2018
It is proposed that due to the increasing incidence of fusariosis and drug resistance, gentamicin components, particularly minor fraction B1 and related aminoglycoside antibiotics, could be tested for their in vivo activity against fusARIosis and aspergillosis either alone or in combination with other antifungal agents. Expand
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Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity
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