Antifouling compounds from the sub-arctic ascidian Synoicum pulmonaria: synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues.

@article{Trpos2014AntifoulingCF,
  title={Antifouling compounds from the sub-arctic ascidian Synoicum pulmonaria: synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues.},
  author={R. Tr{\'e}pos and Gunnar Cervin and C. Hellio and H. Pavia and W. Stensen and Klara Stensv{\aa}g and J. Svendsen and T. Haug and J. Svenson},
  journal={Journal of natural products},
  year={2014},
  volume={77 9},
  pages={
          2105-13
        }
}
The current study describes the antifouling properties of four members belonging to the recently discovered synoxazolidinone and pulmonarin families, isolated from the sub-Arctic sessile ascidian Synoicum pulmonaria collected off the Norwegian coast. Four simplified synthetic analogues were also prepared and included in the study. Several of the studied compounds displayed MIC values in the micro-nanomolar range against 16 relevant marine species involved in both the micro- and macrofouling… Expand

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