Antifertility principle of Ruta graveolens.


Chloroform extracts of the root, stem and leaf of Ruta graveolens L. showed significant anti-fertility activity in rats when administered intragastrically on days 1-10 post-coitum. Fractionation of the extracts led to the isolation of chalepensin as the active component with some toxicity. Time-dosing experiments demonstrated that chalepensin acts at the… (More)


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@article{Kong1989AntifertilityPO, title={Antifertility principle of Ruta graveolens.}, author={Y. C. Kong and C. P. Lau and Karyn Wat and K. H. Ng and Paul Pui-Hay But and K. F. Cheng and Peter Waterman}, journal={Planta medica}, year={1989}, volume={55 2}, pages={176-8} }