Antiepiligrin cicatricial pemphigoid of the larynx successfully treated with a combination of tetracycline and niacinamide.

@article{Sakamoto2002AntiepiligrinCP,
  title={Antiepiligrin cicatricial pemphigoid of the larynx successfully treated with a combination of tetracycline and niacinamide.},
  author={Kikuo Sakamoto and Kazunori Mori and Takashi Hashimoto and Kim B. Yancey and Tadashi Nakashima},
  journal={Archives of otolaryngology--head & neck surgery},
  year={2002},
  volume={128 12},
  pages={1420-3}
}
A case of antiepiligrin cicatricial pemphigoid that primarily involved the larynx and required a tracheostomy was studied. The diagnosis was based on the direct immunofluorescence findings of a biopsy specimen from the glottis, immunofluorescence using normal and 1M sodium chloride-split normal human skin as substrates, and immunoprecipitation. A dramatic clinical improvement was observed after the combined administration of tetracycline hydrochloride and niacinamide. The tracheal stoma could… CONTINUE READING

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