Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.

@article{Temkin2001AntiepileptogenesisAS,
  title={Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.},
  author={Nancy R. Temkin},
  journal={Epilepsia},
  year={2001},
  volume={42 4},
  pages={515-24}
}
PURPOSE To synthesize evidence concerning the effect of antiepileptic drugs (AEDs) for seizure prevention and to contrast their effectiveness for provoked versus unprovoked seizures. METHODS Medline, Embase, and The Cochrane Clinical Trials Register were the primary sources of trials, but all trials found were included. Minimal requirements: seizure-prevention outcome given as fraction of cases; AED or control assigned by random or quasi-random mechanism. Single abstracter. Aggregate relative… CONTINUE READING

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