Antiepileptic treatment in pregnant women: morphological and behavioural effects.

  title={Antiepileptic treatment in pregnant women: morphological and behavioural effects.},
  author={Torbjōrn Tomson and Dina Battino},
  journal={Handbook of experimental pharmacology},
It is well established that children exposed to antiepileptic drugs (AEDs) in utero have an increased risk of adverse pregnancy outcomes including foetal growth retardation, major congenital malformations and impaired postnatal cognitive development. However, due to the significant maternal and foetal risks associated with uncontrolled epileptic seizures, AED treatment is generally maintained during pregnancy in the majority of women with active epilepsy. The prevalence of major malformations… CONTINUE READING
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