Antiepileptic drugs and the regulation of mood and quality of life (QOL): the evidence from epilepsy.

@article{Selai2005AntiepilepticDA,
  title={Antiepileptic drugs and the regulation of mood and quality of life (QOL): the evidence from epilepsy.},
  author={Caroline E Selai and Debbie Bannister and Michael Robert Trimble},
  journal={Epilepsia},
  year={2005},
  volume={46 Suppl 4},
  pages={50-7}
}
We review the literature on the influence of antiepileptic drugs (AEDs) on mood and quality of life in patients with epilepsy. Although many anecdotal reports cover a spectrum of AEDs, most of the controlled data have come from studies of carbamazepine and lamotrigine. Both of these compounds appear to have positive effects on mood, and these data parallel the effects noted in nonepilepsy populations. AEDs that are gamma-aminobutyric acid (GABA)ergic tend to have negative effects on mood, and… CONTINUE READING

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