Antiepileptic drugs and bone metabolism in children: data from 128 patients.

  title={Antiepileptic drugs and bone metabolism in children: data from 128 patients.},
  author={Peter Borusiak and Thorsten Langer and Marion Heruth and Michael Karenfort and Ulrich Bettendorf and Andreas Christoph Jenke},
  journal={Journal of child neurology},
  volume={28 2},
There are conflicting results concerning bone metabolism in children receiving antiepileptic medication, with data concentrating on neurologically impaired patients. We performed a multicenter cross-sectional study in otherwise healthy children who received monotherapy with valproic acid, oxcarbazepine, lamotrigine, sulthiame, levetiracetam, or topiramate for at least 6 months. Data on calcium, phosphorus, alkaline phosphatase, 25-OH vitamin D, and parathormone were collected. Among 128… CONTINUE READING
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