Antidyslipidemic activity of polyprenol from Coccinia grandis in high-fat diet-fed hamster model.

@article{Singh2007AntidyslipidemicAO,
  title={Antidyslipidemic activity of polyprenol from Coccinia grandis in high-fat diet-fed hamster model.},
  author={Geetu Singh and Prasoon Gupta and Preeti S. Rawat and Anju Puri and Gitika Bhatia and Rakesh N. Maurya},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2007},
  volume={14 12},
  pages={792-8}
}
Ethanol extract of Coccinia grandis (L.) Voigt showed significant triglyceride (TG) and cholesterol-lowering effects in dyslipidemic hamster model. Ethanolic extract was fractionated into chloroform, n-butanol and water-soluble fractions and were evaluated. Activity was proved to be concentrated in chloroform-soluble fraction. Chloroform-soluble fraction containing active component was subjected to repeated column chromatography, furnished a polyprenol characterized as C(60)-polyprenol (1… CONTINUE READING
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