Antidotal effects of dimercaptosuccinic acid.

  title={Antidotal effects of dimercaptosuccinic acid.},
  author={G S Ding and Y Y Liang},
  journal={Journal of applied toxicology : JAT},
  volume={11 1},
Dimercaptosuccinic acid (DMS), HOOC-CH(SH)-CH(SH)-COOH, was first developed in China as an effective antidote for poisoning from many heavy metals, such as Pb, Hg, As, Cd, Sb, Tl, Au, Zn, Ni, Pt, Ag, Co and Sn. DMS increases the excretion of Ce, Pm, Sr and Po from the body. Hundreds of patients suffering from hepatolenticular degeneration (Wilson's disease) have been treated successfully with DMS. Recently, DMS was found to be effective also in treating certain non-metallic intoxications, like… CONTINUE READING
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