Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats.

@article{Nwafor2000AntidiarrhoealAA,
  title={Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats.},
  author={Paul Alozie Nwafor and Francis Kanayo Okwuasaba and Liu Binda},
  journal={Journal of ethnopharmacology},
  year={2000},
  volume={72 3},
  pages={
          421-7
        }
}
The effect of methanolic extract of Asparagus pubescens root on experimentally-induced diarrhoea and ulceration was investigated in rats. The extract (500-1500 mg/kg) dose-dependently, reduced significantly the intestinal propulsive movement, castor oil-induced diarrhoea and intestinal fluid accumulation. Yohimbine an alpha(2)-adrenoceptor blocker attenuated the antidiarrhoeal effect of the extract. The extract also reduced the ulcer indices induced by indomethacin and ethanol in a dose-related… CONTINUE READING

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