Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats

@article{Rao2008AntidiarrhoealAO,
  title={Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats},
  author={Chandana Venkateswara Rao and Madhavan Vijayakumar and K. Sairam and Vikas Kumar},
  journal={Journal of Natural Medicines},
  year={2008},
  volume={62},
  pages={396-402}
}
The present study was designed to investigate the antidiarrhoeal potential of 50% ethanolic extract of Cinnamomum tamala on experimentally induced castor oil diarrhoea, gastric emptying of phenol red meal, gastrointestinal transit of charcoal meal and in vitro mast cell degranulation activity. C. tamala extract (25, 50 and 100 mg/kg, orally) produced a dose-dependent reduction in the total amount of faecal matter in castor oil-induced diarrhoea. The mean distance travelled by charcoal meal at… 
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References

SHOWING 1-10 OF 29 REFERENCES
Biochemical studies on the antidiarrhoeal effects of Cauvery-100, an ayurvedic formulation, in rats.
TLDR
The increased gastrointestinal motility in diarrhoea was brought back to near normal levels on the treatment of Cauvery-100, suggesting the protective influence of the drug on the gastrointestinal tract.
Study of antidiarrhoeal activity of four medicinal plants in castor-oil induced diarrhoea.
Delay of castor oil diarrhoea in rats: a new way to evaluate inhibitors of prostaglandin biosynthesis
TLDR
It is concluded that delay of castor oil‐induced diarrhoea in rats allows a detailed characterization of aspirin‐like compounds, and that inhibition of prostaglandin biosynthesis is insufficient to suppress the intestinal effects of the oil.
Enteropooling assay: a test for diarrhea produced by prostaglandins.
Chemical composition of essential oil of Cinnamomum tamala Nees et Eberm. leaves
A hydrodistilled oil obtained from the leaves of Cinnamomum tamala Nees et Eberm., grown in India, was analysed by capillary GC and GC–MS. The leaf volatile oil contained 40 constituents, of which a
Effects of quercetin on the gastrointestinal tract in rats and mice
TLDR
It is suggested that α2‐adrenergic receptors mediate the effect of quercetin on intestinal motility and secretion.
Phenolics and betacyanins in red beetroot (Beta vulgaris) root: distribution and effect of cold storage on the content of total phenolics and three individual compounds.
TLDR
The distribution of total phenolics and main betacyanins in red beetroot (Beta vulgaris) root was determined, and tentative identifications of betanidin and feruloylamaranthin were made.
Influence of aging on gastric emptying of liquids, small intestine transit, and fecal output in rats
Quantitative and Ultrastructural Analysis of Rectal Mucosal Mast Cells in Acute Infectious Diarrhea
TLDR
Findings suggest that mast cell populations are more dense around blood vessels and nerves and thatinflammatory mediators derived from arachidonic acidmetabolites are the response of mast cells to the alterations in diarrhea, despite differences in the etiology ofdiarrhea.
...
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