Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats

  title={Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats},
  author={Chandana Venkateswara Rao and Madhavan Vijayakumar and K. Sairam and Vikas Kumar},
  journal={Journal of Natural Medicines},
The present study was designed to investigate the antidiarrhoeal potential of 50% ethanolic extract of Cinnamomum tamala on experimentally induced castor oil diarrhoea, gastric emptying of phenol red meal, gastrointestinal transit of charcoal meal and in vitro mast cell degranulation activity. C. tamala extract (25, 50 and 100 mg/kg, orally) produced a dose-dependent reduction in the total amount of faecal matter in castor oil-induced diarrhoea. The mean distance travelled by charcoal meal at… 
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