Antidiarrhoeal activity of the ethyl acetate extract of Baphia nitida (Papilionaceae).

@article{Adeyemi2008AntidiarrhoealAO,
  title={Antidiarrhoeal activity of the ethyl acetate extract of Baphia nitida (Papilionaceae).},
  author={Olufunmilayo Olaide Adeyemi and Abidemi J Akindele},
  journal={Journal of ethnopharmacology},
  year={2008},
  volume={116 3},
  pages={
          407-12
        }
}
In our search for plants useful in the treatment of diarrhoea, we investigated the ethyl acetate extract of Baphia nitida (BN) using intestinal transit, enteropooling and gastric emptying tests in mice and rats. In the castor oil intestinal transit test, BN produced a significant (P<0.05) dose dependent decrease in propulsion with peristaltic index (PI) values of 56.85+/-6.76, 36.84+/-3.04 and 31.98+/-2.60%, respectively at doses of 100, 200 and 400mg/kg vs. 89.33+/-6.28% for control. The… CONTINUE READING