Antidiabetic effects and gene expression profiling in obese mice treated with Isaria sinclairii over a 6-month period.

@article{Ahn2010AntidiabeticEA,
  title={Antidiabetic effects and gene expression profiling in obese mice treated with Isaria sinclairii over a 6-month period.},
  author={Mi-young Ahn and Sang Duck Jee and Byung Mu Lee and Ji-hye Yeon and Kun-koo Park and Jae Hwang and Eun Young Yun},
  journal={Journal of toxicology and environmental health. Part A},
  year={2010},
  volume={73 21-22},
  pages={
          1511-20
        }
}
The molecular mechanisms underlying the glucose-lowering effects of Isaria sinclairii (Cicada Dongchunghacho), a fungus cultured on silkworm, are not fully elucidated. Thus the glucose-lowering effects of I. sinclairii as potential an antidiabetic agent were investigated in C57BL/6 obese (ob/ob) mice over a 6-mo period. For a period of 26 wk, ob mice were administered either 5 or 10% (w/w) I. sinclairii powder (IS), 10% dry mulberry leaf powder (ML), or 10% silkworm (SW) powder in the standard… CONTINUE READING
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