Antidiabetic complications and anti-Alzheimer activities of sophoflavescenol, a prenylated flavonol from Sophora flavescens, and its structure-activity relationship.

Abstract

It was previously reported that prenylated flavonols from Sophora flavescens are inhibitors of rat lens aldose reductase (RLAR), human recombinant aldose reductase (HRAR), advanced glycation endproducts (AGE), β-secretase (BACE1) and cholinesterases (ChE). Based upon structure-activity relationships, 3,4'-dihydroxy flavonols with a prenyl or lavandulyl… (More)
DOI: 10.1002/ptr.3326

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@article{Jung2011AntidiabeticCA, title={Antidiabetic complications and anti-Alzheimer activities of sophoflavescenol, a prenylated flavonol from Sophora flavescens, and its structure-activity relationship.}, author={Hyun Ah Jung and Seong Eun Jin and Jun-Seong Park and Jae Sui Choi}, journal={Phytotherapy research : PTR}, year={2011}, volume={25 5}, pages={709-15} }