Antidiabetic cataract effects of GbE, rutin and quercetin are mediated by the inhibition of oxidative stress and polyol pathway.

  title={Antidiabetic cataract effects of GbE, rutin and quercetin are mediated by the inhibition of oxidative stress and polyol pathway.},
  author={Qian Lu and Meng Hao and Wenya Wu and N. Zhang and Adelusi Temitope Isaac and Jiale Yin and X. Zhu and L. Du and Xiaoxing Yin},
  journal={Acta biochimica Polonica},
  volume={65 1},
  • Qian Lu, Meng Hao, +6 authors Xiaoxing Yin
  • Published 2018
  • Chemistry, Medicine
  • Acta biochimica Polonica
  • One of the earliest critical secondary complications of diabetes is the opacification of the eye lens - a condition strictly associated with diabetic cataract. The study presented here was designed to investigate the effect of Ginkgo biloba extract (GbE), rutin and quercetin on streptozotocin (STZ) induced diabetic cataract (DC) rats. Ten weeks after administration of GbE, rutin and quercetin, the opacity of diabetic rats' lenses was graded under a slit lamp. Then, the levels of malondialdehyde… CONTINUE READING
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