• Corpus ID: 89977533

Antidiabetic activity and safety of piper capense, berberis holstii, sonchus asper, vernonia lasiopus and galinsoga parviflora in alloxan-induced diabetic albino mice

@inproceedings{Kimani2017AntidiabeticAA,
  title={Antidiabetic activity and safety of piper capense, berberis holstii, sonchus asper, vernonia lasiopus and galinsoga parviflora in alloxan-induced diabetic albino mice},
  author={Lucy Njeri Kimani},
  year={2017}
}
In Kenya, diabetes mellitus is of health concern to the public, because it causes substantial morbidity, mortality, and long-term complications. Synthetic drugs used in the management of diabetes are unavailable, have numerous side effects and are expensive. Many plants such as Piper capense, Berberis holstii, Sonchus asper, Vernonia lasiopus and Galinsoga parviflora used traditionally to manage many diseases including diabetes mellitus but their efficacy and safety after long-term use are not… 

References

SHOWING 1-10 OF 177 REFERENCES
In Vivo Antidiabetic Effect of Aqueous Leaf Extract of Azardirachta indica, A. juss in Alloxan Induced Diabetic Mice
TLDR
The study confirms the traditional use of this plant part in the treatment of diabetes mellitus, however, organic solvent extraction of the leaves ofThis plant should be done to compare effects of both organic and aqueous fractions.
Antidiabetic and safety of lantana rhodesiensis in alloxan induced diabetic rats
TLDR
The observed hypoglycemic activity and slight toxicity could be associated with the phytonutrients present in this plant.
Hypoglycemic Effect of Lippia javanica in Alloxan Induced Diabetic Mice
TLDR
The results showed that the plant extracts were effective in reducing blood sugar levels and revealed the presence of vital phytochemicals which possess antidiabetic activities.
In-Vivo Antidiabetic Activity and Safety of The Aqueous Stem Bark Extract of Kleinia squarrosa
TLDR
The observed hypoglycemic activity and slight toxicity could be associated with the phytochemicals present in this plant extract.
Hypoglycemic Activity of Some Kenyan Plants Traditionally used to Manage Diabetes Mellitus in Eastern Province
TLDR
It is established that the five bioactive plants can be safely used in the management of diabetes and some plants proved to be highly toxic, mildly toxic and others were safe.
Antidiabetic Effects of Aqueous Leaf Extracts of Acacia nilotica in Alloxan Induced Diabetic Mice
TLDR
The intraperitoneal route of herbal extract administration was found to be more effective than the oral route and qualitative and quantitative phytochemical screening of aqueous leaf extracts of A. nilotica indicated the presence of phenols, alkaloids, flavonoids, tannins and saponins, but cardiac glycosides and phylobatanins were not detected.
Evaluation of hypoglycaemic and hypolipidaemic effects of aqueous ethanolic extracts of Treculia africana Decne and Bryophyllum pinnatum,/i> Lam. and their mixture on streptozotocin (STZ)-induced diabetic rats
TLDR
A significant reduction in both postprandial and STZ-induced diabetes blood glucose levels, triglyceride levels, low density lipoprotein (LDL) level, and increase in high density lipoplatin level were observed, which supports the basis for the herbal use of T. africana and B. pinnatum in the management of diabetes and heart diseases.
Anti-diabetic effects of Allium cepa (onions) aqueous extracts on alloxan-induced diabetic Rattus novergicus
TLDR
A. cepa studied exhibited promising hypoglycaemic and hypolipidaemic activity in alloxan-induced diabetic rats, which could represent a protective mechanism against the development of hyperglycaemia and hyperlipidaemia characteristic of diabetes mellitus.
Hypoglycemic Activity of Aqueous and Ethylacetate Leaf and Stem Bark Extracts of Pappea capensis in Alloxan-Induced Diabetic BALB/c Mice
TLDR
P. capensis is a nutritious plant whose ethylacetate extracts possess in vivo hypoglycemic activity, which was similar to that of glibenclamide at 3 mg/kg body weight from the second to the twenty-fourth hour.
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