Antidepressive-drug-induced bodyweight gain is associated with polymorphisms in genes coding for COMT and TPH1.

@article{Secher2009AntidepressivedruginducedBG,
  title={Antidepressive-drug-induced bodyweight gain is associated with polymorphisms in genes coding for COMT and TPH1.},
  author={Anna Secher and Jens Bukh and Camilla Bock and Pernille Koefoed and Henrik Berg Rasmussen and Thomas M Werge and Lars Vedel Kessing and Erling Mellerup},
  journal={International clinical psychopharmacology},
  year={2009},
  volume={24 4},
  pages={199-203}
}
Bodyweight gain is a common side effect of treatment with antidepressive drugs; however, little is known about the mechanisms behind this weight gain. Genetic differences may contribute to the susceptibility for bodyweight gain during antidepressive treatment. The objective of this study was to examine the association of antidepressive-drug-induced bodyweight gain with polymorphisms in genes within the serotonin or catecholamine systems. Participants (N = 165) were selected from the Danish… CONTINUE READING

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