Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years

@article{dosSantos2016AntidepressiveAA,
  title={Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years},
  author={Rafael Guimar{\~a}es dos Santos and Fl{\'a}via de Lima Os{\'o}rio and Jos{\'e} Alexandre S. Crippa and Jordi Riba and Antonio Waldo Zuardi and Jaime E.C. Hallak},
  journal={Therapeutic Advances in Psychopharmacology},
  year={2016},
  volume={6},
  pages={193 - 213}
}
To date, pharmacological treatments for mood and anxiety disorders and for drug dependence show limited efficacy, leaving a large number of patients suffering severe and persistent symptoms. Preliminary studies in animals and humans suggest that ayahuasca, psilocybin and lysergic acid diethylamide (LSD) may have antidepressive, anxiolytic, and antiaddictive properties. Thus, we conducted a systematic review of clinical trials published from 1990 until 2015, assessing these therapeutic… 

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