Antidepressant use in clinical practice: efficacy v. effectiveness.

  title={Antidepressant use in clinical practice: efficacy v. effectiveness.},
  author={John Donoghue and Timothy R. Hylan},
  journal={The British journal of psychiatry. Supplement},
BACKGROUND Although the efficacy of antidepressants has been demonstrated in randomised, controlled clinical trials, it is how an antidepressant is used in clinical practice that determines its clinical effectiveness, or real-world efficacy. AIMS To explore the frequency with which antidepressants are used at adequate dose and duration to obtain remission of symptoms and prevent relapse in clinical practice and discuss potential implications for clinical outcomes. METHOD Studies of… CONTINUE READING

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