Antidepressant-like effects of the vasopressin V1b receptor antagonist SSR149415 in the Flinders Sensitive Line rat

@article{Overstreet2005AntidepressantlikeEO,
  title={Antidepressant-like effects of the vasopressin V1b receptor antagonist SSR149415 in the Flinders Sensitive Line rat},
  author={David H. Overstreet and G. E. Griebel},
  journal={Pharmacology Biochemistry and Behavior},
  year={2005},
  volume={82},
  pages={223-227}
}
There is an increased interest in the potential of vasopressin receptor antagonists as antidepressants because of the involvement of vasopressin in stress-related behavioral changes. The present study sought to provide confirmatory evidence for the antidepressant-like effects of the selective vasopressin V1b receptor antagonist SSR149415, which had been previously demonstrated in a variety of animal models. The Flinders Sensitive Line (FSL) rat, a selectively bred animal model of depression… CONTINUE READING
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