Antidepressant-like effects of aniracetam in aged rats and its mode of action

  title={Antidepressant-like effects of aniracetam in aged rats and its mode of action},
  author={Kazuo Nakamura and Yushiro Tanaka},
Rationale: Aniracetam has been reported to be efficacious for treating poststroke depression, but no studies that basically examined the antidepressive effects have been made. Objective: We aimed to test the antidepressant-like property of aniracetam in rats and to clarify the mechanisms of action through the interaction studies with some receptor antagonists. Methods: Antidepressant-like effects of aniracetam and various classes of compounds including different antidepressants were examined in… CONTINUE READING
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