Antidepressant-like effect of Kyllinga brevifolia rhizomes in male mice and chemical characterization of the components of the active ethyl acetate fraction.

  title={Antidepressant-like effect of Kyllinga brevifolia rhizomes in male mice and chemical characterization of the components of the active ethyl acetate fraction.},
  author={Mar{\'i}a C. Helli{\'o}n-Ibarrola and Yenny Montalbetti and O. Heinichen and Mar{\'i}a L. Kennedy and M A Campuzano and N L Alvarenga and Derlis A. Ibarrola},
  journal={Journal of ethnopharmacology},
ETHNO-PHARMACOLOGICAL RELEVANCE Kyllinga brevifolia rhizomes (Cyperaceae) are used in Paraguayan traditional medicine as a refreshing beverage, and is claimed to own digestive, diuretic, sedative, tonic, antispasmodic and sudorific properties. [...] Key Method Treatments in all modalities were made 1h before swimming test. The KbF-ethyl-ac was analyzed by LC-DAD-ESI-MS and LC-ESI-MS/MS in order to identify the active components. Expand
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Evaluation of Anti-Aggressive Activity of Kyllinga brevifolia in Rodent Model of Aggression
Findings suggest that Kyllinga brevifolia exhibits a general anti-offensive aggressive activity and may be relevant in the treatment of reactive aggression in humans.
The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice.
An anxiolytic-like profile of action for the extract of Aloysia polystachya without sedative side effect is indicated, being this activity probably mediated by other mechanism than BDZ-bs modulation at the GABA(A) receptors.
Evaluation of hepatoprotective activity of Kyllinga nemoralis (Hutch & Dalz) rhizomes.
The study identified a plant with potential hepatoprotective constituents which will be isolated and characterized in future.
Sedative properties of the decoction of the rhizome of Cyperus articulatus.
Observations suggest that the rhizome of C. articulatus has pharmacological properties similar to those of sedatives, which probably explain at least part of the therapeutic efficiency claimed for this plant in traditional medicine.
Acute toxicity and general pharmacological effect on central nervous system of the crude rhizome extract of Kyllinga brevifolia Rottb.
The crude hydro-alcoholic rhizome extract of Kyllinga brevifolia Rottb, a popular medicine used in Paraguay, was investigated on mice and produced a significant increase in the hypnotic effect induced by pentobarbital in a dose-dependent manner.
Behavioral, neurochemical and neuroendocrine effects of the ethanolic extract from Curcuma longa L. in the mouse forced swimming test.
Results suggested that antidepressant properties of the ethanolic extract of Curcuma longa was mediated through regulations of neurochemical and neuroendocrine systems and it may be a useful agent against depression.
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Results indicate an antidepressant-like profile of action for the hydro-ethanolic extract and the component(s) of the ethyl acetate fraction obtained from A. polystachya, which deserve further investigation.