Antidepressant-like components of Hypericum perforatum extracts: an overview of their pharmacokinetics and metabolism.

Abstract

Extracts of Hypericum perforatum are becoming increasingly popular for the treatment of mild to moderate depression, despite the lack of consensus on their efficacy. Although the mechanism(s) of this action are still debated, several components, including the naphthodianthrones hypericin and pseudohypericin, the acylphloroglucinol hyperforin and some… (More)

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