Antidepressant-like behavioral and neurochemical effects of the citrus-associated chemical apigenin.

@article{Yi2008AntidepressantlikeBA,
  title={Antidepressant-like behavioral and neurochemical effects of the citrus-associated chemical apigenin.},
  author={Li-Tao Yi and Jian-Mei Li and Yu-Cheng Li and Ying Pan and Qun Xu and Lingdong Kong},
  journal={Life sciences},
  year={2008},
  volume={82 13-14},
  pages={741-51}
}
Apigenin is one type of bioflavonoid widely found in citrus fruits, which possesses a variety of pharmacological actions on the central nervous system. A previous study showed that acute intraperitoneal administration of apigenin had antidepressant-like effects in the forced swimming test (FST) in ddY mice. To better understand its pharmacological activity, we investigated the behavioral effects of chronic oral apigenin treatment in the FST in male ICR mice and male Wistar rats exposed to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 68 references

Similar Papers

Loading similar papers…