Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.

@article{Zeni2011AntidepressantlikeAN,
  title={Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.},
  author={Ana L{\'u}cia Bertarello Zeni and Andr{\'e}a Dias Elpo Zomkowski and Tharine Aparecida Dal-Cim and Marcelo Maraschin and Ana L{\'u}cia S Rodrigues and Carla In{\^e}s Tasca},
  journal={Journal of ethnopharmacology},
  year={2011},
  volume={137 1},
  pages={
          864-74
        }
}
ETHNOPHARMACOLOGICAL RELEVANCE Aloysia gratissima (Gill. et Hook) Tronc. (Verbenaceae) is used traditionally for the treatment of headache, bronchitis, and nervous systems disorders including depression. AIM OF THE STUDY To investigate the antidepressant-like and neuroprotective effects of Aloysia gratissima aqueous extract (AE) and the involvement of l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. MATERIALS AND METHODS The antidepressant-like effect of AE was… CONTINUE READING
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