Antidepressant exposure may protect against decrement in frontal gray matter volumes in geriatric depression.

@article{Lavretsky2005AntidepressantEM,
  title={Antidepressant exposure may protect against decrement in frontal gray matter volumes in geriatric depression.},
  author={Helen Lavretsky and Donna J Roybal and Martina Ballmaier and Arthur W. Toga and Anand Kumar},
  journal={The Journal of clinical psychiatry},
  year={2005},
  volume={66 8},
  pages={964-7}
}
OBJECTIVES Depressed elderly patients with and without antidepressant exposure were compared to normal controls to examine the effects of prior antidepressant exposure on regional brain gray matter volumes using magnetic resonance imaging (MRI). METHOD The study was conducted from October 1999 to January 2003. Patients and controls were closely matched by age and education. They underwent comprehensive neuropsychiatric and physical examinations. Measures of the total frontal lobe and the… CONTINUE READING
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