Antidepressant effects of high and low frequency repetitive transcranial magnetic stimulation to the dorsolateral prefrontal cortex: a double-blind, randomized, placebo-controlled trial.

@article{Stern2007AntidepressantEO,
  title={Antidepressant effects of high and low frequency repetitive transcranial magnetic stimulation to the dorsolateral prefrontal cortex: a double-blind, randomized, placebo-controlled trial.},
  author={William M. Stern and Jos{\'e} Mar{\'i}a Tormos and Daniel Z. Press and Chester Pearlman and Alvaro Pascual-Leone},
  journal={The Journal of neuropsychiatry and clinical neurosciences},
  year={2007},
  volume={19 2},
  pages={179-86}
}
Repetitive transcranial magnetic stimulation (rTMS) has antidepressant effects in patients with major depressive disorder. The mechanisms of action and optimal stimulation parameters remain unclear. To test the hypothesis that rTMS exerts antidepressant effects either by enhancing left dorsolateral prefrontal cortex (DLPFC) excitability or by decreasing right DLPFC excitability, the authors studied 45 patients with unipolar recurrent major depressive disorder in a double-blind, randomized… CONTINUE READING
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