Antidepressant effects of carbamazepine.

  title={Antidepressant effects of carbamazepine.},
  author={Robert M Post and Thomas W. Uhde and Peter P. Roy-Byrne and Russell T. Joffe},
  journal={The American journal of psychiatry},
  volume={143 1},
Thirty-five depressed patients diagnosed by DSM-III criteria participated in a double-blind study of the acute antidepressant effects of the anticonvulsant carbamazepine, at average doses of 971 mg/day, achieving mean +/- SD blood levels of 9.3 +/- 1.9 micrograms/ml (range, 3-12.5 micrograms/ml). Twenty patients (57%) showed at least mild improvement, and 12 showed more substantial improvement. Possible clinical predictors of antidepressant response to carbamazepine are discussed. These… CONTINUE READING

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