Antidepressant effects of Soyo-san on Immobilization stress in ovariectomized female rats.

@article{Oh2007AntidepressantEO,
  title={Antidepressant effects of Soyo-san on Immobilization stress in ovariectomized female rats.},
  author={Jin Kyung Oh and Yoon-Sang Kim and H S Park and E Lim and K S Pyun and Insop Shim},
  journal={Biological & pharmaceutical bulletin},
  year={2007},
  volume={30 8},
  pages={1422-6}
}
Soyo-san is a traditional oriental medicinal formula, a mixture of 9 crude drugs, and it has been clinically used for treating mild depressive disorders. The purpose of the study was to examine the effect of Soyo-san on repeated stress-induced alterations of learning and memory on a Morris water maze (MWM) task and also the anxiety-related behavior on the elevated pulse maze (EPM) in ovariectomized female rats. We assessed the changes in the reactivity of the cholinergic system by measuring the… CONTINUE READING