Antidepressant effect of extracts from Ginkgo biloba leaves in behavioral models.

@article{Sakakibara2006AntidepressantEO,
  title={Antidepressant effect of extracts from Ginkgo biloba leaves in behavioral models.},
  author={Hiroyuki Sakakibara and Kaori Ishida and Oliver Grundmann and Jun-ichiro Nakajima and Shujiro Seo and Veronika Butterweck and Yuko Minami and Satomi Saito and Yoshichika Kawai and Yutaka Nakaya and Junji Terao},
  journal={Biological \& pharmaceutical bulletin},
  year={2006},
  volume={29 8},
  pages={
          1767-70
        }
}
Extracts of Ginkgo biloba (EGB) are a complex product prepared from green leaves of the Ginkgo biloba tree. In the present study, the antidepressant effect of EGB was examined using two behavioral models, the forced swimming test (FST) in rats and tail suspension test (TST) in mice. EGB significantly reduced immobility time in the FST at a dosage of 10 and 50 mg/kg body weight after repeated oral treatment for 14 d, although no change of motor dysfunction was observed with the same dosage in… Expand
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