Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test

@article{Reneric1998AntidepressantBE,
  title={Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test},
  author={J. P. Reneric and Irwin Lucki},
  journal={Psychopharmacology},
  year={1998},
  volume={136},
  pages={190-197}
}
 Because of clinical interest in the effects of antidepressant drugs that exert their effects on multiple neurotransmitter systems, the behavioral effects produced by combined treatment with an SSRI (fluoxetine) with a selective norepinephrine (NE; desipramine) or dopamine (DA) reuptake inhibitor (buproprion) were examined in the forced swimming test (FST), a behavioral test in rodents that predicts the clinical activity of antidepressants. Three additional compounds with mixed activity as NE-5… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 97 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

LY248686, A New Inhibitor of Serotonin and Norepinephrine Uptake

Neuropsychopharmacology • 1993
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…