Antidepressant-associated mood-switching and transition from unipolar major depression to bipolar disorder: a review.


OBJECTIVES Compare reported rates of mood-shifts from major depression to mania/hypomania/mixed-states during antidepressant (AD)-treatment and rates of diagnostic change from major depressive disorder (MDD) to bipolar disorder (BPD). METHODS Searching computerized literature databases, followed by summary analyses. RESULTS In 51 reports of patients… (More)
DOI: 10.1016/j.jad.2012.10.033


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