Antidepressant-associated maniform states in acute treatment of patients with bipolar-I depression

  title={Antidepressant-associated maniform states in acute treatment of patients with bipolar-I depression},
  author={Ronald Bottlender and Daniel Rudolf and Anton Strauss and Hans-J{\"u}rgen M{\"o}ller},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
Abstract Medical records of 158 patients with bipolar depression were analysed for the incidence of a switch from depression to maniform states (mania and hypomania). Relation to psychopharmacological treatment was investigated. Thirty-nine (25%) patients of the total sample had switched to a maniform state during the treatment period in the hospital. Among that group the phenomenon occurred in 23 patients (15%) as a hypomania and in 16 patients (10%) as a mania. Patients with a switch were… Expand
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