Antidepressant Use in the Elderly

@article{Goldberg1997AntidepressantUI,
  title={Antidepressant Use in the Elderly},
  author={Richard J. Goldberg},
  journal={Drugs \& Aging},
  year={1997},
  volume={11},
  pages={119-131}
}
SummaryDepression is a significant problem in the elderly. Because of aging-related pharmacokinetic and pharmacodynamic changes, it is not possible to automatically extrapolate findings on the efficacy or tolerability of antidepressants from younger to older populations.Venlafaxine inhibits both noradrenaline (norepinephrine) and serotonin (5-hydroxytryptamine; 5-HT) reuptake. Analysis of data from phase II and III trials showed that venlafaxine was comparably effective in the young and in a… Expand
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