Anticonvulsants for soman-induced seizure activity.

  title={Anticonvulsants for soman-induced seizure activity.},
  author={Tsung-Ming Shih and John H. McDonough and Irwin Koplovitz},
  journal={Journal of biomedical science},
  volume={6 2},
This report describes studies of anticonvulsants for the organophosphorus (OP) nerve agent soman: a basic research effort to understand how different pharmacological classes of compounds influence the expression of seizure produced by soman in rats, and a drug screening effort to determine whether clinically useful antiepileptics can modulate soman-induced seizures in rats. Electroencephalographic (EEG) recordings were used in these studies. Basic studies were conducted in rats pretreated with… CONTINUE READING
47 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 47 extracted citations

Similar Papers

Loading similar papers…