• Corpus ID: 8958426

Anticonvulsant and behavioral actions of triterpene isolated from Rubia cordifolia Linn.

@article{Kasture2000AnticonvulsantAB,
  title={Anticonvulsant and behavioral actions of triterpene isolated from Rubia cordifolia Linn.},
  author={Veena Sanjay Kasture and Vinayak Kashinath Deshmukh and Chandrabhan Tukaram Chopde},
  journal={Indian journal of experimental biology},
  year={2000},
  volume={38 7},
  pages={
          675-80
        }
}
Effect of a triterpene isolated from the acetone soluble part of petroleum ether extract of R. cordifolia was studied on convulsions induced by maximum electro shock (MES), electrical kindling and various chemoconvulsants in rats and mice. The effect of triterpene was also investigated on behavior and gamma-aminobutyric acid (GABA) and serotonin (5-HT) content in mouse brain. Triterpene inhibited seizures induced by MES, electrical kindling, pentylenetetrazol (PTZ), and lithium-pilocarpine… 
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