Anticoagulation in combined membrane/adsorption systems.

  title={Anticoagulation in combined membrane/adsorption systems.},
  author={Jens Hartmann and Karin Strobl and D. Falkenhagen},
  volume={29 2},
For extracorporeal blood purification treatments, an effective anticoagulation is needed to avoid contact activation via the intrinsic pathway of the blood-clotting system. While heparin is the standard anticoagulant in dialysis, it shows some disadvantages which have to be considered when it is used in membrane/adsorption-based blood purification systems. An alternative option for anticoagulation in these systems is citrate, which is effective as an anticoagulant by reducing the ionized… CONTINUE READING