Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention.

  title={Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention.},
  author={Charles Seth Landefeld and Rebecca J Beyth},
  journal={The American journal of medicine},
  volume={95 3},
OBJECTIVE To review (1) the clinical epidemiology of bleeding during anticoagulant therapy with heparin or warfarin, (2) data useful in estimating the risk for bleeding in individual patients, and (3) the efficacy of methods for its prevention. METHODS Relevant literature was identified by a computerized search of the Medline database and by review of the bibliographies of original and review articles. Studies were classified according to their design. Estimates of the risk for bleeding… CONTINUE READING
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