Anticoagulant activity of enzymatically synthesized amylose derivatives containing carboxy or sulfonate groups.

Abstract

Heparin is an extracellular matrix polysaccharide. It is widely employed as an anticoagulant and can be used to form an anticoagulant surface on various medical devices such as renal dialysis devices to prevent thrombosis. However, heparin may cause hemorrhage and thrombocytopenia. Moreover, commercially available heparin may be contaminated with viruses… (More)
DOI: 10.1016/j.actbio.2010.02.052

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