Anticlastogenic effect of aqueous extracts of Agaricus blazei on CHO-k1 cells, studying different developmental phases of the mushroom.

@article{Bellini2003AnticlastogenicEO,
  title={Anticlastogenic effect of aqueous extracts of Agaricus blazei on CHO-k1 cells, studying different developmental phases of the mushroom.},
  author={Marilanda Ferreira Bellini and N L Giacomini and Augusto Ferreira da Eira and L{\'u}cia Regina Ribeiro and M{\'a}rio S{\'e}rgio Mantovani},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2003},
  volume={17 4},
  pages={465-9}
}
The Agaricus blazei Murill (ABM) mushroom, known as the sun mushroom, is native to Brazil and has become known for its medicinal properties. This study examined the anticlastogenic effect of Agaricus blazei in Chinese hamster ovary cells, CHO-k1, by means of a chromosome aberration test using methyl methanesulphonate (MMS, 10(-4)M) as the DNA damage inducing agent. Two mushroom lines were used, ABM 99/26 and ABM 97/11, and the latter was used in the young (Y) and sporulating (S) developmental… CONTINUE READING

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